When glucose cannot be utilized appropriately by the liver, muscle, or other cells and tissues, glucose starts to be stored as fat in your adipose tissue.
In times of cellular stress, glucose control changes. Part of the Cell Danger Response is to increase inflammation. Inflammation results in reduced Triiodothyronine (T3) production reaching the nucleus of your cells, and a state of cellular hypothyroidism. With reduced levels of thyroid hormone, it is more difficult for glucose to get into the cells. All glucose transport proteins require T3 inside the cell for optimal function and transport of glucose. As T3 levels drop at a cellular level under stress, there is reduced transport of glucose into most of your cells (except for fat cells). Cells become more insulin and glucose resistant, causing glucose to accumulate within the blood, or to be converted into fat.
As cells and tissues become resistant to glucose and insulin, your body begins to manufacture glucose from stored fat. This results in the rise of blood triglyceride levels and the development of fatty liver.
How do you know if you have a blood glucose problem? If you have been diagnosed with insulin resistance, pre-diabetes, diabetes, metabolic syndrome, or fatty liver disease your blood glucose is not regulating properly and cellular stress and/or cellular hypothyroidism is likely part of the problem.
Hi, I’m Dr. Eric Balcavage, owner and founder of Rejuvagen. If you’re struggling with health issues or have questions, let’s chat. You can schedule a 15-minute call with me to get started.